The 23rd Dutch-German Joint Meeting brings together experts in molecular cardiology to discuss disease mechanisms and therapeutic advances across cardiovascular pathologies. This edition prominently features early- and mid-career investigators to bring fresh perspectives alongside established expertise.
Vascular and metabolic contributions to cardiomyopathies and heart failure; advanced human modelling for disease and repair; arrhythmia pathways and therapeutic frontiers in gene, drug, and wearable strategies.
Prof. Andrew Baker, Edinburgh and Prof. Jolanda Kluin, Rotterdam
New University (NU) building Vrije Universiteit Amsterdam
De Boelelaan 1111
1081 HV Amsterdam
The Netherlands
| 12:00 – 12:45 | Arrival, Coffee and Snacks |
| 12:45 – 13:00 | Welcome and Organizational Matters |
| 13:00 – 14:30 | Session 1: The Vascular Side of Heart Failure Chairs: Reinier Boon (Amsterdam, NL); Friederike Cuello (Hamburg, DE) Speakers: Jeffrey Kroon (Amsterdam, NL); Immunometabolic Modulation of Vascular Interfaces to Reshape the Cardiometabolic Microenvironment Guillermo Luxan (Frankfurt, DE); The Role of Microvasculature in Heart Failure Dimitri Kasakovski (Maastricht, NL); Adventitial Fibroblasts in Vascular Ageing and Fibrosis Maike Frye: Angiocrine control of cardiac function |
| 14:30 – 15:00 | Coffee Break |
| 15:00 – 16:30 | Session 2: Therapeutic Frontiers in Cardiovascular Disease Chairs: Geert Boink (Amsterdam, NL); Gabriele Schiattarella (Berlin, DE) Speakers: Francesca Stillitano (Utrecht, NL); Gene Therapy for PLN-R14del cardiomyopathy Constanze Schmidt (Göttingen, DE); A New Concept to Modulate Cardiac Conductivity Miranda van Eck (Leiden, NL); ABCA1 in Bone Marrow-Derived Cells as a Modulator of Atherosclerosis Wolfgang Linke (Munster, DE); Evidence-based Treatment Strategies for Titin Truncation Cardiomyopathy |
| 16:30 – 18:00 | Poster Session I (with coffee and snacks) |
| 18:00 – 19:00 | Keynote lecture 1 Introducer: Monika Gladka (Amsterdam, NL) Andrew Baker, Edinburgh; Developing advanced therapies for vascular disease: The journey and the future |
| 20:00 | Dinner and Evening event |
| 09:30 – 11:00 | Session 3: Mechanisms and Management of Cardiomyopathies Chairs: Herman Sillje (Groningen, NL); Chair 2: TBA Speakers: Peter-Paul Zwetsloot (Rotterdam, NL); Individual Response Measurements in Cardiomyopathies and Targeted Therapies Claudia Crocini (Berlin, DE); Effect of Myosin Activators on hiPSC-derived Cardiomyocytes Expressing a Lamin A Mutation Associated with Dilated Cardiomyopathy Connie Bezzina (Amsterdam, NL); Mapping the Genomic Landscape of Inherited Cardiomyopathies Brenda Gerull (Würzburg, DE); Contributions of the Immune System to Arrhythmogenic Cardiomyopathy |
| 11:00 – 11:30 | Coffee Break |
| 11:30 – 12:30 | Session 4: Young Investigator Award Jury: Leon de Windt (Maastricht, NL); Mirko Volkers (Heidelberg, DE); Carol Ann Remme (Amsterdam, NL); Friederike Cuello (Hamburg, DE) Speakers:TBA |
| 12:30 – 13:30 | Lunch |
| 13:30 – 15:00 | Session 5: Decoding Patterns and Pathways in Cardiac Arrhythmias Chairs: Toon van Veen (Utrecht, NL); Larissa Fabritz (Hamburg, DE) Speakers: Matthijs Cluitmans (Maastricht, NL); The Circle of Reentry: Understanding the Components of (Unexplained) Sudden Cardiac Arrest Viviane Timmermann (Freiburg, DE); Illuminating Mechanisms: From Fluorescent Sarcomeres to Identifiable Models of Arrhythmia Dynamics Daniël Pijnappels (Leiden, NL); Wearable-based Shock-free Control of Cardiac Rhythm Katharina Scherschel (Dusseldorf, DE); Beyond the Usual Suspects: The Role of Neuro-Glial Pathways in Cardiac Arrhythmias |
| 15:00 – 16:30 | Poster Session II (with coffee and snacks) |
| 16:30 – 18:00 | Session 6: New Approach Methodologies in CV disease Chairs: Harsha Devalla (Amsterdam, NL); Katrin Streckfuß-Bömeke (Würzburg, DE) Speakers: Jan Willem Buikema (Amsterdam, NL); The Molecular Keys Unlocking Cardiomyocyte Proliferation Lika Drakhlis (Hannover, DE); Heart-forming Organoids for Modeling Human Development and Disease Robert Passier (Enschede, NL); Engineering Predictive Human Cardiac Systems. From Stem Cells to Functional Disease Models Michael Stauske (AstraZeneca, Sweden); Industry Perspective on Implementation of Human Models in Cardiovascular Drug Discovery Giulia Campostrini (Leiden, NL); Better together: multicellular 3D cardiac microtissues for an improved hiPSC-based disease modelling |
| 18:00 – 19:00 | Keynote lecture 2 Introducer: TBA Jolanda Kluin, Rotterdam. Surgeon-scientist, the road less traveled by |
| 20:00 | Dinner and Evening event |
| 09:30 – 11:00 | Session 7: Metabolic Drivers and Modifiers of Cardiovascular Disease Chairs: Jolanda van der Velden (Amsterdam, NL); Chair 2: Benjamin Meder (Heidelberg, DE) Speakers: Signe Mosegaard (Amsterdam, NL); Molecular Insights to Metabolic Cardiomyopathies Alexander Bartelt (Munich, DE); Molecular Stress Resilience in the Heart Mariette Boon (Rotterdam, NL); The Intricate Link Between Obesity and Cardiovascular Disease Christoph Maack (Würzburg, DE); Mechano-energetic Uncoupling in Heart Failure Julia Ritterhoff (Heidelberg, DE); Cardiac Fatty Acid Oxidation in Health & Disease – More Than a Fuel |
| 11:00 – 11:30 | Coffee Break |
| 11:30 – 13:00 | Session 8: Rewiring Repair: Dynamics of Cardiovascular Regeneration Chairs: Eva van Rooij (Utrecht, NL); Laura Zelarayan-Behrend (Gießen, DE) Speakers: Arica Beisaw (Heidelberg, DE); Cardiomyocyte-macrophage Crosstalk During Zebrafish Heart Regeneration Marie-Jose Goumans (Leiden, NL); Cardiac Repair XB: An Outer Body Experience Tim Koopmans (Utrecht, NL); Mechanical Uncoupling Facilitates Cardiac Repair in Adult Spiny Mice Christian Bär (Hannover, DE); Targeting Telomerase in Cardiopulmonary Disease and Regeneration |
| 13:00 – 13:15 | Award Announcements |
| 13:15 – 13:30 | Announcement next year venue |
| 13:30 | Takeaway Lunch and Departure |
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